A comparison between power line noise level field measurements and man-made radio noise prediction curves in the high frequency radio band

Radio frequency noise is often the limiting factor in the ability of a communications receiver to discern a desired signal from man made interference. The predominate man made radio noise source in the high frequency radio band is gap type breakdown discharges on electric power distribution lines. The International Radio Consultative Committee (CCIR) has published its Report 258 which predicts the level of man made radio noise in the business, residential, rural, and quiet rural environmental categories. This thesis compares field measurements of gap type breakdown discharge generated noise, made in the high and very high frequency radio bands, to CCIR Report 258 predictions. It is shown that CCIR noise-level predictions correspond to field measurements in the low end of the high frequency band. At higher frequencies the CCIR curve consistently predicts a lower noise level than was measured in the field. An explanation for the difference between field measurements and CCIR predictions is presented. A trend noticed in the noise amplitude versus receiver bandwidth data measurements is investigated and leads to the development of a receiver bandwidth adjustment matrix. Using this matrix the noise-power measurements made in one receiver bandwidth can be scaled to a different bandwidth.http://archive.org/details/acomparisonbetwe109457457U.S. Marine Corps (U.S.M.C.) author

Prostate-specific antigen bounce predicts for a favorable prognosis following brachytherapy: a meta-analysis.

PURPOSE: Controversy exists whether the prostate-specific antigen (PSA) bounce phenomenon following definitive radiation for prostate cancer has prognostic significance. Here, we perform a meta-analysis to determine the association between PSA bounce and biochemical control after brachytherapy alone. MATERIAL AND METHODS: We reviewed Medline, EMBASE, and CENTRAL citations through February 2012. Studies that recorded biochemical failure rates in bouncers and non-bouncers were included. Hazard ratios describing the impact of bounce on biochemical failure were extracted directly from the studies or calculated from survival curves. Pooled estimates were obtained using the inverse variance method. A random effects model was used in cases of significant effect heterogeneity (p \u3c 0.10 using Q test). RESULTS: The final analysis included 3011 patients over 6 studies treated with brachytherapy. Meta-analysis revealed that patients experiencing PSA bounce after brachytherapy, conferred a decreased risk of biochemical failure (random effects model HR = 0.42, 95% CI: 0.30-0.59; p \u3c 0.001). CONCLUSIONS: Our meta-analysis determined that PSA bounce predicts for improved biochemical control following brachytherapy. To our knowledge, this is the first study describing this effect

A Functional Role for ADAM10 in Human Immunodeficiency Virus Type-1 Replication

<p>Abstract</p> <p>Background</p> <p>Gene trap insertional mutagenesis was used as a high-throughput approach to discover cellular genes participating in viral infection by screening libraries of cells selected for survival from lytic infection with a variety of viruses. Cells harboring a disrupted <it>ADAM10 </it>(A Disintegrin and Metalloprotease 10) allele survived reovirus infection, and subsequently ADAM10 was shown by RNA interference to be important for replication of HIV-1.</p> <p>Results</p> <p>Silencing ADAM10 expression with small interfering RNA (siRNA) 48 hours before infection significantly inhibited HIV-1 replication in primary human monocyte-derived macrophages and in CD4⁺cell lines. In agreement, ADAM10 over-expression significantly increased HIV-1 replication. ADAM10 down-regulation did not inhibit viral reverse transcription, indicating that viral entry and uncoating are also independent of ADAM10 expression. Integration of HIV-1 cDNA was reduced in ADAM10 down-regulated cells; however, concomitant 2-LTR circle formation was not detected, suggesting that HIV-1 does not enter the nucleus. Further, ADAM10 silencing inhibited downstream reporter gene expression and viral protein translation. Interestingly, we found that while the metalloprotease domain of ADAM10 is not required for HIV-1 replication, ADAM15 and γ-secretase (which proteolytically release the extracellular and intracellular domains of ADAM10 from the plasma membrane, respectively) do support productive infection.</p> <p>Conclusions</p> <p>We propose that ADAM10 facilitates replication at the level of nuclear trafficking. Collectively, our data support a model whereby ADAM10 is cleaved by ADAM15 and γ-secretase and that the ADAM10 intracellular domain directly facilitates HIV-1 nuclear trafficking. Thus, ADAM10 represents a novel cellular target class for development of antiretroviral drugs.</p

Copper(II) tetrakis(pentafluorophenyl)-β-octachloroporphyrin

The title compound, {4,5,9,10,14,15,19,20-octachloro-2,7,12, 17-tetrakis(pentafluorophenyl)-20,22,23,24- tetraazapentacyclo[l6.2.l.1^(3·6).l^(8·11).l^(13·16)]tetracosa-1,3(21),4,6,8(22),9,11, 13(23), 14, 16, 18(24), 19-dodecaene}copper(II)(CuTFPPC1_8)dichloromethane solvate, shows a large tetrahedral distortion or ruffling, with pairs of Cl atoms alternately averaging + 1.20 and -1.18 Å out of the plane of the four N atoms; the Cu atom is 0.01 Å out of the plane and the N atoms show a slight (±0.12 Å) tetrahedral distortion. A Cl atom of the solvent, at 3.515 (6) Å in an approximately axial position, is the closest non-bonded neighbor of the Cu atom

Perceived coach autonomy support, basic need satisfaction and the well- and ill-being of elite youth soccer players: A longitudinal investigation

Objectives: Drawing from the Basic Needs Theory [BNT; Ryan, R. M., & Deci, E. L. (2002). An overview of self-determination theory. In E. L. Deci & R. M. Ryan (Eds.), Handbook of self-determination research (pp. 3-33). Rochester, NY: University of Rochester Press], the major purpose of the present study was to test a hypothesized sequence of temporal relationships between perceptions of coach autonomy support, basic need satisfaction and indices of well- and ill-being. A subsidiary aim was to ascertain the assumed mediational role of basic need satisfaction in explicating the perceived autonomy support and well-/ill-being relationships over time.\ud \ud Method: Participants (N = 54 males) from an elite youth soccer academy in the UK completed a multi-section questionnaire tapping the targeted variables on six occasions across two competitive seasons.\ud \ud Results: Multi-level regression analyses revealed that perceptions of coach autonomy support positively predicted within-person changes and between-person mean differences in basic need satisfaction and well-being over time. \ud \ud Satisfaction scores for the needs for competence and relatedness were found to predict within-person changes in subjective vitality. These same needs partially mediated the coach autonomy support-subjective vitality link over the two seasons.\ud \ud Conclusions: The findings partially support the tenets of BNT, and are discussed in terms of their practical application to participants involved in an elite youth sport setting. \u

Prospectus, May 10, 1984

COPIES ARE AVAILABLE FOR \u27IMAGES\u27; StuGo election results; Staerkel talks about scholarships; News Digest; Letter to the editor: Separate Women\u27s Program vital for the women who have invested so much in you; PC Happenings; Hard work recognized by Dean; Letter from the editor: Human element was always there; Editor says goodbye; \u27Intellectual Freedom Begins Here\u27; Student art exhibit displayed variety; Everyone enjoys four-day week during summer session; Law clerk tells how the judicial system really works; Eddie Albert plots ready to grow; Cribbet to speak at Commencement; Students and organizations honored at awards banquet; Creative Corner...Especially for you!!; Freedom; Cathy; This is Dedicated to Amy; Too Late; Almost There; Unwritten; The Life and Death of a Friendship; Parkland\u27s year the was--83/84--awards, scholarships, sports and fun; Classifieds; Did you know...; International songwriters competition; College Bowl National; Pretenders release latest and Rock Goddess their first; \u27Sixteen Candles\u27 burns out; Films show promise this summer; Winter wind blows hot; \u27Indiana Jones\u27 and \u27Spock\u27 lead the way at movies; Instructor receives award; Spring Out; StuGo purchases new van; Sports Digest; N.A.I.A. kills plan; 1984 Parkland outdoor track bests; L.A. students try to trust the Olympics; Baseball team ends season; 1984 Graduates and Candidates for Graduationhttps://spark.parkland.edu/prospectus_1984/1021/thumbnail.jp

“Click-fluors”: triazole-linked saccharide sensors

A series of boronic acid-containing saccharide receptors was synthesised via copper catalysed azide–alkyne cycloaddition (CuAAC) reactions.</p

Copper(II) tetrakis(pentafluorophenyl)-β-octachloroporphyrin

The title compound, {4,5,9,10,14,15,19,20-octachloro-2,7,12, 17-tetrakis(pentafluorophenyl)-20,22,23,24- tetraazapentacyclo[l6.2.l.1^(3·6).l^(8·11).l^(13·16)]tetracosa-1,3(21),4,6,8(22),9,11, 13(23), 14, 16, 18(24), 19-dodecaene}copper(II)(CuTFPPC1_8)dichloromethane solvate, shows a large tetrahedral distortion or ruffling, with pairs of Cl atoms alternately averaging + 1.20 and -1.18 Å out of the plane of the four N atoms; the Cu atom is 0.01 Å out of the plane and the N atoms show a slight (±0.12 Å) tetrahedral distortion. A Cl atom of the solvent, at 3.515 (6) Å in an approximately axial position, is the closest non-bonded neighbor of the Cu atom